Taking Methyl Folate for MTHFR C667T mutation

Three and one-half months have passed. I've been methylating and having amazing results. I take a nutritional supplement, Methyl CpG,with breakfast. I has 2000 mcg of methyl folate and 1000 mcg methyl B12. in the evening I take Thorne Basic B which contains 400 mcg methyl folate and 200 mcg methyl B12 plus additional B vitamins. If I start feeling that deep exhaustion, I'll add about 1250 mcg methyl B12 lozenge. I break up a 5000 mcg tab into 4 pieces and let one peice dissolve under my tongue.

It took a week or so figure out how much to take. My doc gave me a sample of the prescription drug, Deplin 15. I took one a day, I was flying my the end of day 3. I was looney. Playing bridge with some friends, I just couldn't focus. Too much Deplin was weird. Everyone noticed. But I didn't do anything extreme or peculiar. The next day I cut back to the Methyl CpG and seemed to find a balance.

My doc told me I didn't need much. She was so right.

In the past 14 weeks, here are the results I've seen:

• Not feeling the deep exhaustion.
• Seldom take naps, whereas before methylation supplementation I was taking 2-3 hour naps 2-4 days a week. I may still nap at times, but only 20-30 minutes 1-2 days a week.
• My vision has dramatically improved. At the eye doctor's, I can read two lines lower than I did last year. I find this amazing.
• Not as anxious. One day I missed taking my morning supplement and began to feel that old familiar body agitation and anxiety. But fortunately, within 20 minutes of taking methyl folate, I was back to my MTHFR-adjusted self.
• Stayed awake and active with dinner guests until 11 pm. I only yawned once and didn't feel drained, anxious, and eager for them to say their goodbyes.
• I approach day-to-day chores with calm and clarity. 
• I no longer feel overwhelmed by too much to do.
• I am setting up more social activities for us than before. I now have the energy and interest to go out 3-5 nights a week. Before methylation 2 nights a week was max. My husband loves to socialize and to go places, so he's more content. And I'm finding that I love it.
• My hair is growing faster, so are my fingernails.
• Had white bumps on upper arms for years - like whitheads - they're gone.
• More muscle tone and stamina.

As I read back through my journal, my body took a while - between 2-3 months to adjust. plus my brain and being have taken a while to adjust to methylation. I had ups and downs, doubt and reassurances. But today, I'm quite pleased. And joyous.

The MTHFR mutation - methylation deficiency

What? A genetic mutation could affect my personal health and well being? Not only that but I received a double dose, meaning the mutation at my MTHFR gene is homozygous, I received one copy from my mother and one from my father. This inherited error means that I have "methylation deficiency". After hours of research and googling, I have learned that thwarts many of my metabolic processes and explains many of my odd body things - I get weird if the dentist gives me laughing gas. I have moments of seeming depressed or maniac, but I'm not really. I'm often tired such that I eagerly nap for a couple hours a day even though I sleep soundly at night. I have a plethora of odd allergies to foods, inhalants, chemicals, dogs and cats and more. It explains why there are at least 3 alcoholics out of 7 members in my family of origin. and why my mother had extreme anemia, yet the B12 she took (cyanocobalamine) didn't give her more energy. But had she been given methylcobalamin, she may have been healthy and energetic.

The mutation explains why my son who also has 2 mutated genes (homozygous)- one from his dad and one from me  - was born with learning disabilities and ADHD. 

Now my challenge is to do what it akes to methylate myself.